Circulating endothelial cell-derived extracellular vesicles mediate the acute phase response and sickness behaviour associated with CNS inflammation

Brain injury elicits a systemic acute-phase response (APR), which is responsible for co-ordinating the peripheral immunological response to injury. To date, the mechanisms responsible for signalling the presence of injury or disease to selectively activate responses in distant organs were unclear. C...

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Publicado no:Sci Rep
Main Authors: Couch, Yvonne, Akbar, Naveed, Roodselaar, Jay, Evans, Matthew C., Gardiner, Chris, Sargent, Ian, Romero, Ignacio A., Bristow, Adrian, Buchan, Alastair M., Haughey, Norman, Anthony, Daniel C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575066/
https://ncbi.nlm.nih.gov/pubmed/28851955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09710-3
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