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Lipopolysaccharide-binding protein (LBP) reverses the amyloid state of fibrin seen in plasma of type 2 diabetics with cardiovascular co-morbidities

Type 2 diabetes (T2D) has many cardiovascular complications, including a thrombotic propensity. Many such chronic, inflammatory diseases are accompanied (and may be exacerbated, and possibly even largely caused) by amyloid fibril formation. Recognising that there are few strong genetic associations...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Pretorius, Etheresia, Mbotwe, Sthembile, Kell, Douglas B.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574907/
https://ncbi.nlm.nih.gov/pubmed/28851981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09860-4
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