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Inhibition of Amebic Lysosomal Acidification Blocks Amebic Trogocytosis and Cell Killing

Entamoeba histolytica ingests fragments of live host cells in a nibbling-like process termed amebic trogocytosis. Amebic trogocytosis is required for cell killing and contributes to tissue invasion, which is a hallmark of invasive amebic colitis. Work done prior to the discovery of amebic trogocytos...

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Udgivet i:mBio
Main Authors: Gilmartin, Allissia A., Ralston, Katherine S., Petri, William A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574710/
https://ncbi.nlm.nih.gov/pubmed/28851845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01187-17
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