Vaccination with poly(D,L-lactide-co-glycolide) nanoparticles loaded with soluble Leishmania antigens and modified with a TNFα-mimicking peptide or monophosphoryl lipid A confers protection against experimental visceral leishmaniasis

Visceral leishmaniasis (VL) persists as a major public health problem, and since the existing chemotherapy is far from satisfactory, development of an effective vaccine emerges as the most appropriate strategy for confronting VL. The development of an effective vaccine relies on the selection of the...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Margaroni, Maritsa, Agallou, Maria, Athanasiou, Evita, Kammona, Olga, Kiparissides, Costas, Gaitanaki, Catherine, Karagouni, Evdokia
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574665/
https://ncbi.nlm.nih.gov/pubmed/28883727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S141069
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