Apolipoprotein L1 risk variants associate with prevalent atherosclerotic disease in African American systemic lupus erythematosus patients

OBJECTIVE: Atherosclerosis is exaggerated in African American (AA) systemic lupus erythematosus (SLE) patients, with doubled cardiovascular disease (CVD) risk compared to White patients. The extent to which common Apolipoprotein L1 (APOL1) risk alleles (RA) contribute to this trend is unknown. This...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Blazer, Ashira, Wang, Binhuan, Simpson, Danny, Kirchhoff, Tomas, Heffron, Sean, Clancy, Robert M., Heguy, Adriana, Ray, Karina, Snuderl, Matija, Buyon, Jill P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574561/
https://ncbi.nlm.nih.gov/pubmed/28850570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182483
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