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Differential analysis between somatic mutation and germline variation profiles reveals cancer-related genes

A major aim of cancer genomics is to pinpoint which somatically mutated genes are involved in tumor initiation and progression. We introduce a new framework for uncovering cancer genes, differential mutation analysis, which compares the mutational profiles of genes across cancer genomes with their n...

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Publicat a:Genome Med
Autors principals: Przytycki, Pawel F., Singh, Mona
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574113/
https://ncbi.nlm.nih.gov/pubmed/28841835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-017-0465-6
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