USH2A Gene Editing Using the CRISPR System

Usher syndrome (USH) is a rare autosomal recessive disease and the most common inherited form of combined visual and hearing impairment. Up to 13 genes are associated with this disorder, with USH2A being the most prevalent, due partially to the recurrence rate of the c.2299delG mutation. Excluding h...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Fuster-García, Carla, García-García, Gema, González-Romero, Elisa, Jaijo, Teresa, Sequedo, María D., Ayuso, Carmen, Vázquez-Manrique, Rafael P., Millán, José M., Aller, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573797/
https://ncbi.nlm.nih.gov/pubmed/28918053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.08.003
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