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Reconstitution of highly purified saxitoxin-sensitive Na+-channels into planar lipid bilayers.

Highly purified Na+-channels isolated from rat brain have been reconstituted into virtually solvent-free planar lipid bilayer membranes. Two different types of electrically excitable channels were detected in the absence of any neurotoxins. The activity of both channels was blocked by saxitoxin. The...

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Publicat a:EMBO J
Autors principals: Hanke, W, Boheim, G, Barhanin, J, Pauron, D, Lazdunski, M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1984
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC557379/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6325173/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1984.tb01839.x
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