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Reconstitution of highly purified saxitoxin-sensitive Na+-channels into planar lipid bilayers.

Highly purified Na+-channels isolated from rat brain have been reconstituted into virtually solvent-free planar lipid bilayer membranes. Two different types of electrically excitable channels were detected in the absence of any neurotoxins. The activity of both channels was blocked by saxitoxin. The...

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Detalhes bibliográficos
Main Authors: Hanke, W, Boheim, G, Barhanin, J, Pauron, D, Lazdunski, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC557379/
https://ncbi.nlm.nih.gov/pubmed/6325173
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