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Genetic Bases of Bicuspid Aortic Valve: The Contribution of Traditional and High-Throughput Sequencing Approaches on Research and Diagnosis

Bicuspid aortic valve (BAV) is a common (0.5–2.0% of general population) congenital heart defect with increased prevalence of aortic dilatation and dissection. BAV has an autosomal dominant inheritance with reduced penetrance and variable expressivity. BAV has been described as an isolated trait or...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Giusti, Betti, Sticchi, Elena, De Cario, Rosina, Magi, Alberto, Nistri, Stefano, Pepe, Guglielmina
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573733/
https://ncbi.nlm.nih.gov/pubmed/28883797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00612
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