Identification of a cDNA clone encoding a mature blood stage antigen of Plasmodium falciparum by immunization of mice with bacterial lysates.

A cDNA library was constructed in pBR322 using mRNA from blood stages of a Papua New Guinean isolate of Plasmodium falciparum. Expression of parasite antigens was not directly detectable by conventional immunological assays. To circumvent this, mice were immunized with lysates of cDNA clones, and th...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Coppel, R L, Brown, G V, Mitchell, G F, Anders, R F, Kemp, D J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1984
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC557358/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6370681/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1984.tb01820.x
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