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HIV-1 envelope glycoprotein stimulates viral transcription and increases the infectivity of the progeny virus through the manipulation of cellular machinery

During HIV infection, large amounts of progeny viral particles, including infectious virus and a large proportion of defective viral particles, are produced. Despite of the critical role of the infectious viruses in infection and pathogenesis in vivo, whether and how those defective viral particles,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ran, Xiaozhuo, Ao, Zhujun, Trajtman, Adriana, Xu, Wayne, Kobinger, Gary, Keynan, Yoav, Yao, Xiaojian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573355/
https://ncbi.nlm.nih.gov/pubmed/28842659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10272-7
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