Plasmodium falciparum GPCR-like receptor SR25 mediates extracellular K(+) sensing coupled to Ca(2+) signaling and stress survival

The malaria parasite Plasmodium falciparum is exposed, during its development, to major changes of ionic composition in its surrounding medium. We demonstrate that the P. falciparum serpentine-like receptor PfSR25 is a monovalent cation sensor capable of modulating Ca(2+) signaling in the parasites....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Moraes, Miriam S., Budu, Alexandre, Singh, Maneesh K., Borges-Pereira, Lucas, Levano-Garcia, Julio, Currà, Chiara, Picci, Leonardo, Pace, Tomasino, Ponzi, Marta, Pozzan, Tullio, Garcia, Célia R. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573319/
https://ncbi.nlm.nih.gov/pubmed/28842684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09959-8
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