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Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway

Zrt/Irt-like proteins (ZIPs) play fundamental roles in metal metabolism/homeostasis and are broadly involved in numerous physiological and pathological processes. The lack of high-resolution structure of the ZIPs hinders understanding of the metal transport mechanism. We report two crystal structure...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Zhang, Tuo, Liu, Jian, Fellner, Matthias, Zhang, Chi, Sui, Dexin, Hu, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573306/
https://ncbi.nlm.nih.gov/pubmed/28875161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1700344
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