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Proteostasis control by the unfolded protein response

Stress induced by accumulation of misfolded proteins in the endoplasmic reticulum (ER) is observed in many physiological and pathological conditions. To cope with ER stress, cells activate the unfolded protein response (UPR), a dynamic signaling network that orchestrates the recovery of homeostasis...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Cell Biol
Prif Awduron: Hetz, Claudio, Chevet, Eric, Oakes, Scott A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573253/
https://ncbi.nlm.nih.gov/pubmed/26239530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3221
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