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Neglected role of hydrogen sulfide in sulfur mustard poisoning: Keap1 S-sulfhydration and subsequent Nrf2 pathway activation

Sulfur mustard (SM) is a chemical warfare agent and a terrorism choice that targets various organs and tissues, especially lung tissues. Its toxic effects are tightly associated with oxidative stress. The signaling molecule hydrogen sulfide (H(2)S) protects the lungs against oxidative stress and act...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Meng, Wenqi, Pei, Zhipeng, Feng, Yongwei, Zhao, Jie, Chen, Yongchun, Shi, Wenwen, Xu, Qingqiang, Lin, Fengwu, Sun, Mingxue, Xiao, Kai
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572733/
https://ncbi.nlm.nih.gov/pubmed/28842592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09648-6
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