Responses of renal hemodynamics and tubular functions to acute sodium–glucose cotransporter 2 inhibitor administration in non-diabetic anesthetized rats

The aim of this study is to examine the effects of acute administration of luseogliflozin, the sodium–glucose cotransporter 2 (SGLT2) inhibitor, on renal hemodynamics and tubular functions in anesthetized non-diabetic Sprague Dawley (SD) rats and 5/6 nephrectomized (Nx) SD rats. Renal blood flow (RB...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ansary, Tuba M., Fujisawa, Yoshihide, Rahman, Asadur, Nakano, Daisuke, Hitomi, Hirofumi, Kobara, Hideki, Masaki, Tsutomu, Titze, Jens M., Kitada, Kento, Nishiyama, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572725/
https://ncbi.nlm.nih.gov/pubmed/28842583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09352-5
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