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Dimerization in tailoring uptake efficacy of the HSV-1 derived membranotropic peptide gH625

gH625 constitutes a promising delivery vehicle for the transport of therapeutic biomacromolecules across membrane barriers. We report an application of multivalency to create a complex nanosystem for delivery and to elucidate the mechanism of peptide-lipid bilayer interactions. Multivalency may offe...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Falanga, Annarita, Valiante, Salvatore, Galdiero, Emilia, Franci, Gianluigi, Scudiero, Olga, Morelli, Giancarlo, Galdiero, Stefania
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572722/
https://ncbi.nlm.nih.gov/pubmed/28842580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09001-x
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