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Neuroprotective effect of kinin B1 receptor activation in acute cerebral ischemia in diabetic mice

Activation of the kallikrein-kinin system enhances cardiac and renal tolerance to ischemia. Here we investigated the effects of selective agonists of kinin B1 or B2 receptor (R) in brain ischemia-reperfusion in diabetic and non-diabetic mice. The role of endogenous kinins was assessed in tissue kall...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Desposito, Dorinne, Zadigue, Georges, Taveau, Christopher, Adam, Clovis, Alhenc-Gelas, François, Bouby, Nadine, Roussel, Ronan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572700/
https://ncbi.nlm.nih.gov/pubmed/28842604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09721-0
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