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Prolonged overexpression of Wnt10b induces epidermal keratinocyte transformation through activating EGF pathway

Wnt10b is a signaling protein regulating skin development and homeostasis, and the expression of Wnt10b is restricted to epidermal keratinocytes in embryonic and postnatal skin. Recent studies indicate an elevated expression of Wnt10b in skin tumors. However, how Wnt10b regulates skin tumorigenesis...

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Detalhes bibliográficos
Publicado no:Histochem Cell Biol
Main Authors: Lei, Mingxing, Lai, Xiangdong, Bai, Xiufeng, Qiu, Weiming, Yang, Tian, Liao, Xiaoling, Chuong, Cheng-Ming, Yang, Li, Lian, Xiaohua, Zhong, Julia Li
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572676/
https://ncbi.nlm.nih.gov/pubmed/25995040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00418-015-1330-6
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