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Specific detection of DNA and RNA targets using a novel isothermal nucleic acid amplification assay based on the formation of a three-way junction structure

The formation of DNA three-way junction (3WJ) structures has been utilised to develop a novel isothermal nucleic acid amplification assay (SMART) for the detection of specific DNA or RNA targets. The assay consists of two oligonucleotide probes that hybridise to a specific target sequence and, only...

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Bibliografiske detaljer
Main Authors: Wharam, Susan D., Marsh, Peter, Lloyd, John S., Ray, Trevor D., Mock, Graham A., Assenberg, René, McPhee, Julie E., Brown, Philip, Weston, Anthony, Cardy, Donald L. N.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC55724/
https://ncbi.nlm.nih.gov/pubmed/11376166
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