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Pervasive coexpression of spatially proximal genes is buffered at the protein level

Genes are not randomly distributed in the genome. In humans, 10% of protein‐coding genes are transcribed from bidirectional promoters and many more are organised in larger clusters. Intriguingly, neighbouring genes are frequently coexpressed but rarely functionally related. Here we show that coexpre...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Main Authors: Kustatscher, Georg, Grabowski, Piotr, Rappsilber, Juri
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572396/
https://ncbi.nlm.nih.gov/pubmed/28835372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20177548
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