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Logic Modeling in Quantitative Systems Pharmacology

Here we present logic modeling as an approach to understand deregulation of signal transduction in disease and to characterize a drug's mode of action. We discuss how to build a logic model from the literature and experimental data and how to analyze the resulting model to obtain insights of re...

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Vydáno v:CPT Pharmacometrics Syst Pharmacol
Hlavní autoři: Traynard, Pauline, Tobalina, Luis, Eduati, Federica, Calzone, Laurence, Saez‐Rodriguez, Julio
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572374/
https://ncbi.nlm.nih.gov/pubmed/28681552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12225
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