Comparative Analysis of 3D Bladder Tumor Spheroids Obtained by Forced Floating and Hanging Drop Methods for Drug Screening

Introduction: Cell-based assays using three-dimensional (3D) cell cultures may reflect the antitumor activity of compounds more accurately, since these models reproduce the tumor microenvironment better. Methods: Here, we report a comparative analysis of cell behavior in the two most widely employed...

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Bibliographic Details
Published in:Front Physiol
Main Authors: Amaral, Robson L. F., Miranda, Mariza, Marcato, Priscyla D., Swiech, Kamilla
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572239/
https://ncbi.nlm.nih.gov/pubmed/28878686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00605
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