Whole-genome sequencing revealed novel prognostic biomarkers and promising targets for therapy of ovarian clear cell carcinoma

BACKGROUND: Ovarian clear cell carcinoma (OCCC) is mostly resistant to standard chemotherapy that results in poor patient survival. To understand the genetic background of these tumours, we performed whole-genome sequencing of OCCC tumours. METHODS: Tumour tissue samples and matched blood samples we...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Br J Cancer
Main Authors: Itamochi, Hiroaki, Oishi, Tetsuro, Oumi, Nao, Takeuchi, Satoshi, Yoshihara, Kosuke, Mikami, Mikio, Yaegashi, Nobuo, Terao, Yasuhisa, Takehara, Kazuhiro, Ushijima, Kimio, Watari, Hidemichi, Aoki, Daisuke, Kimura, Tadashi, Nakamura, Toshiaki, Yokoyama, Yoshihito, Kigawa, Junzo, Sugiyama, Toru
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Genetics & Genomics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572180/
https://ncbi.nlm.nih.gov/pubmed/28728166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.228
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