Nuclear expression of Gli-1 is predictive of pathologic complete response to chemoradiation in trimodality treated oesophageal cancer patients

BACKGROUND: Predictive biomarkers or signature(s) for oesophageal cancer (OC) patients undergoing preoperative therapy could help administration of effective therapy, avoidance of ineffective ones, and establishment new strategies. Since the hedgehog pathway is often upregulated in OC, we examined i...

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Veröffentlicht in:Br J Cancer
Hauptverfasser: Wadhwa, Roopma, Wang, Xuemei, Baladandayuthapani, Veerabhadran, Liu, Bin, Shiozaki, Hironori, Shimodaira, Yusuke, Lin, Quan, Elimova, Elena, Hofstetter, Wayne L, Swisher, Stephen G, Rice, David C, Maru, Dipen M, Kalhor, Neda, Bhutani, Manoop S, Weston, Brian, Lee, Jeffrey H, Skinner, Heath D, Scott, Ailing W, Kaya, Dilsa Mizrak, Harada, Kazuto, Berry, Donald, Song, Shumei, Ajani, Jaffer A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Translational Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5572179/
https://ncbi.nlm.nih.gov/pubmed/28728163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.225
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