CHOP favors endoplasmic reticulum stress-induced apoptosis in hepatocellular carcinoma cells via inhibition of autophagy

C/EBP-homologous protein (CHOP) is an important component of the endoplasmic reticulum (ER) stress response. We demonstrated the induction of ER stress in response to tunicamycin stimulation, as evidenced by increased expression of chaperone proteins Grp78, Grp94, and enhanced eukaryotic initiation...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Lei, Yan, Wang, Shuiliang, Ren, Bingshuang, Wang, Jin, Chen, Jin, Lu, Jun, Zhan, Shihuai, Fu, Yunfeng, Huang, Lianghu, Tan, Jianming
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571976/
https://ncbi.nlm.nih.gov/pubmed/28841673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183680
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