CHOP favors endoplasmic reticulum stress-induced apoptosis in hepatocellular carcinoma cells via inhibition of autophagy

C/EBP-homologous protein (CHOP) is an important component of the endoplasmic reticulum (ER) stress response. We demonstrated the induction of ER stress in response to tunicamycin stimulation, as evidenced by increased expression of chaperone proteins Grp78, Grp94, and enhanced eukaryotic initiation...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lei, Yan, Wang, Shuiliang, Ren, Bingshuang, Wang, Jin, Chen, Jin, Lu, Jun, Zhan, Shihuai, Fu, Yunfeng, Huang, Lianghu, Tan, Jianming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571976/
https://ncbi.nlm.nih.gov/pubmed/28841673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183680
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