CHOP favors endoplasmic reticulum stress-induced apoptosis in hepatocellular carcinoma cells via inhibition of autophagy

C/EBP-homologous protein (CHOP) is an important component of the endoplasmic reticulum (ER) stress response. We demonstrated the induction of ER stress in response to tunicamycin stimulation, as evidenced by increased expression of chaperone proteins Grp78, Grp94, and enhanced eukaryotic initiation...

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Опубликовано в: :PLoS One
Главные авторы: Lei, Yan, Wang, Shuiliang, Ren, Bingshuang, Wang, Jin, Chen, Jin, Lu, Jun, Zhan, Shihuai, Fu, Yunfeng, Huang, Lianghu, Tan, Jianming
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571976/
https://ncbi.nlm.nih.gov/pubmed/28841673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183680
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