Microbiome balance in sputum determined by PCR stratifies COPD exacerbations and shows potential for selective use of antibiotics

BACKGROUND: While a subgroup of patients with exacerbations of chronic obstructive pulmonary disease (COPD) clearly benefit from antibiotics, their identification remains challenging. We hypothesised that selective assessment of the balance between the two dominant bacterial groups (Gammaproteobacte...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Haldar, Koirobi, Bafadhel, Mona, Lau, Kelvin, Berg, Adam, Kwambana, Brenda, Kebadze, Tatiana, Ramsheh, Mohammadali Yavari, Barker, Bethan, Haldar, Pranabashis, Johnston, Sebastian, Ketley, Julian M., Brightling, Christopher E., Barer, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571965/
https://ncbi.nlm.nih.gov/pubmed/28841671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182833
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