Microbiome balance in sputum determined by PCR stratifies COPD exacerbations and shows potential for selective use of antibiotics

BACKGROUND: While a subgroup of patients with exacerbations of chronic obstructive pulmonary disease (COPD) clearly benefit from antibiotics, their identification remains challenging. We hypothesised that selective assessment of the balance between the two dominant bacterial groups (Gammaproteobacte...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Haldar, Koirobi, Bafadhel, Mona, Lau, Kelvin, Berg, Adam, Kwambana, Brenda, Kebadze, Tatiana, Ramsheh, Mohammadali Yavari, Barker, Bethan, Haldar, Pranabashis, Johnston, Sebastian, Ketley, Julian M., Brightling, Christopher E., Barer, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571965/
https://ncbi.nlm.nih.gov/pubmed/28841671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182833
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