Microbiome balance in sputum determined by PCR stratifies COPD exacerbations and shows potential for selective use of antibiotics

BACKGROUND: While a subgroup of patients with exacerbations of chronic obstructive pulmonary disease (COPD) clearly benefit from antibiotics, their identification remains challenging. We hypothesised that selective assessment of the balance between the two dominant bacterial groups (Gammaproteobacte...

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Vydáno v:PLoS One
Hlavní autoři: Haldar, Koirobi, Bafadhel, Mona, Lau, Kelvin, Berg, Adam, Kwambana, Brenda, Kebadze, Tatiana, Ramsheh, Mohammadali Yavari, Barker, Bethan, Haldar, Pranabashis, Johnston, Sebastian, Ketley, Julian M., Brightling, Christopher E., Barer, Michael R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571965/
https://ncbi.nlm.nih.gov/pubmed/28841671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182833
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