Systematic analysis of telomere length and somatic alterations in 31 cancer types

Cancer cells survive cellular crisis through telomere maintenance mechanisms. We report telomere lengths in 18,430 samples, including tumors and non-neoplastic samples, across 31 cancer types. Tumor telomeres were shorter compared to normal tissues, and longer in sarcomas and gliomas compared to oth...

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Veröffentlicht in:Nat Genet
Hauptverfasser: Barthel, Floris P., Wei, Wei, Tang, Ming, Martinez-Ledesma, Emmanuel, Hu, Xin, Amin, Samirkumar B., Akdemir, Kadir C., Seth, Sahil, Song, Xingzhi, Wang, Qianghu, Lichtenberg, Tara, Hu, Jian, Zhang, Jianhua, Zheng, Siyuan, Verhaak, Roel G.W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571729/
https://ncbi.nlm.nih.gov/pubmed/28135248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3781
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