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Identifying pleiotropic genes in genome-wide association studies from related subjects using the linear mixed model and Fisher combination function
BACKGROUND: A multivariate genome-wide association test is proposed for analyzing data on multivariate quantitative phenotypes collected from related subjects. The proposed method is a two-step approach. The first step models the association between the genotype and marginal phenotype using a linear...
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| Publicado no: | BMC Bioinformatics |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5571642/ https://ncbi.nlm.nih.gov/pubmed/28836938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1791-9 |
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