Reduced expression of let‐7f activates TGF‐β/ALK5 pathway and leads to impaired ischaemia‐induced neovascularization after cigarette smoke exposure

This study sought to determine the potential role of microRNAs (miRNAs) in the detrimental effects of cigarette smoke on angiogenesis and neovascularization. Using large‐scale miRNA profiling and qRT‐PCR analyses, we identified let‐7f as a pro‐angiogenic miRNA which expression is significantly reduc...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Dhahri, Wahiba, Dussault, Sylvie, Haddad, Paola, Turgeon, Julie, Tremblay, Sophie, Rolland, Kevin, Desjarlais, Michel, Cáceres‐Gorriti, Katia Y, Mathieu, Raphael, Rivard, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571564/
https://ncbi.nlm.nih.gov/pubmed/28345812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13144
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