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NKG2D ligand RAE1ε induces generation and enhances the inhibitor function of myeloid‐derived suppressor cells in mice

Expression of surface NKG2D ligands on tumour cells, which activates nature killer (NK) cells and CD8(+) T cells, is crucial in antitumour immunity. Some types of tumours have evolved mechanisms to suppress NKG2D‐mediated immune cell activation, such as tumour‐derived soluble NKG2D ligands or sustai...

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Bibliographic Details
Published in:J Cell Mol Med
Main Authors: Qian, Li, Liu, Yang, Wang, Shaoqing, Gong, Weijuan, Jia, Xiaoqin, Liu, Lu, Ye, Feng, Ding, Jingjuan, Xu, Yuwei, Fu, Yi, Tian, Fang
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571551/
https://ncbi.nlm.nih.gov/pubmed/28276625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13124
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