Persistent distention of colon damages interstitial cells of Cajal through Ca(2+)‐ERK‐AP‐1‐miR‐34c‐SCF deregulation

Gastrointestinal motility disorders (GMDs) are attributed to loss of interstitial cells of Cajal (ICC), whose survival and function are deeply dependent on the activation of KIT/SCF signalling. Based on the facts that gastrointestinal distention is common in GMD patients and SCF produced by smooth m...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Yang, Shu, Dong, Fang, Li, Dandan, Sun, Haimei, Wu, Bo, Sun, Tingyi, Wang, Yaxi, Shen, Ping, Ji, Fengqing, Zhou, Deshan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571545/
https://ncbi.nlm.nih.gov/pubmed/28580775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13108
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