Development, functional characterization and validation of methodology for GMP-compliant manufacture of phagocytic macrophages: A novel cellular therapeutic for liver cirrhosis

BACKGROUND AIMS: Autologous macrophage therapy represents a potentially significant therapeutic advance for the treatment of severe progressive liver cirrhosis. Administration of macrophages has been shown to reduce inflammation and drive fibrotic scar breakdown and tissue repair in relevant models....

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Detalhes bibliográficos
Publicado no:Cytotherapy
Main Authors: Fraser, Alasdair R., Pass, Chloe, Burgoyne, Paul, Atkinson, Anne, Bailey, Laura, Laurie, Audrey, W.A. McGowan, Neil, Hamid, Akib, Moore, Joanna K., Dwyer, Benjamin J., Turner, Marc L., Forbes, Stuart J., Campbell, John D.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Cell Production
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571439/
https://ncbi.nlm.nih.gov/pubmed/28673774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcyt.2017.05.009
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