Identification and Mode of Action of a Plant Natural Product Targeting Human Fungal Pathogens

Candida albicans is a major cause of fungal diseases in humans, and its resistance to available drugs is of concern. In an attempt to identify novel antifungal agents, we initiated a small-scale screening of a library of 199 natural plant compounds (i.e., natural products [NPs]). In vitro susceptibi...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Dorsaz, Stéphane, Snäkä, Tiia, Favre-Godal, Quentin, Maudens, Pierre, Boulens, Nathalie, Furrer, Pascal, Ebrahimi, Samad Nejad, Hamburger, Matthias, Allémann, Eric, Gindro, Katia, Queiroz, Emerson Ferreira, Riezman, Howard, Wolfender, Jean-Luc, Sanglard, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571344/
https://ncbi.nlm.nih.gov/pubmed/28674054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00829-17
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