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Rapid and Consistent Evolution of Colistin Resistance in Extensively Drug-Resistant Pseudomonas aeruginosa during Morbidostat Culture

Colistin is a last-resort antibiotic commonly used against multidrug-resistant strains of Pseudomonas aeruginosa. To investigate the potential for in situ evolution of resistance against colistin and to map the molecular targets of colistin resistance, we exposed two P. aeruginosa isolates to colist...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Dößelmann, Bianca, Willmann, Matthias, Steglich, Matthias, Bunk, Boyke, Nübel, Ulrich, Peter, Silke, Neher, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571341/
https://ncbi.nlm.nih.gov/pubmed/28630206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00043-17
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