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Subinhibitory Concentrations of Trimethoprim and Sulfamethoxazole Prevent Biofilm Formation by Acinetobacter baumannii through Inhibition of Csu Pilus Expression

Acinetobacter baumannii is emerging as a multidrug-resistant nosocomial pathogen of increasing threat to human health worldwide. Pili are important bacterial virulence factors, playing a role in attachment to host cells and biofilm formation. The Csu pilus, which is assembled via the chaperone-usher...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Moon, Ki Hwan, Weber, Brent S., Feldman, Mario F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571315/
https://ncbi.nlm.nih.gov/pubmed/28674047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00778-17
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