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Influence of Mitochondrial Genetics on the Mitochondrial Toxicity of Linezolid in Blood Cells and Skin Nerve Fibers

The antibiotic linezolid is a ribosomal inhibitor with excellent efficacy. Although the administration period has been reduced to 28 days, side effects, usually of hematologic or neuropathic origin, are still reported due to secondary inhibition of mitochondrial protein synthesis. Susceptibility to...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Garrabou, G., Soriano, À., Pinós, T., Casanova-Mollà, J., Pacheu-Grau, D., Morén, C., García-Arumí, E., Morales, M., Ruiz-Pesini, E., Catalán-Garcia, M., Milisenda, J. C., Lozano, E., Andreu, A. L., Montoya, J., Mensa, J., Cardellach, F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571298/
https://ncbi.nlm.nih.gov/pubmed/28674062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00542-17
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