Preferential Targeting of Conserved Gag Regions after Vaccination with a Heterologous DNA Prime-Modified Vaccinia Virus Ankara Boost HIV-1 Vaccine Regimen

Prime-boost vaccination strategies against HIV-1 often include multiple variants for a given immunogen for better coverage of the extensive viral diversity. To study the immunologic effects of this approach, we characterized breadth, phenotype, function, and specificity of Gag-specific T cells induc...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Bauer, Asli, Podola, Lilli, Mann, Philipp, Missanga, Marco, Haule, Antelmo, Sudi, Lwitiho, Nilsson, Charlotta, Kaluwa, Bahati, Lueer, Cornelia, Mwakatima, Maria, Munseri, Patricia J., Maboko, Leonard, Robb, Merlin L., Tovanabutra, Sodsai, Kijak, Gustavo, Marovich, Mary, McCormack, Sheena, Joseph, Sarah, Lyamuya, Eligius, Wahren, Britta, Sandström, Eric, Biberfeld, Gunnel, Hoelscher, Michael, Bakari, Muhammad, Kroidl, Arne, Geldmacher, Christof
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2017
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571275/
https://ncbi.nlm.nih.gov/pubmed/28701395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00730-17
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