A Biomimetic Microfluidic Tumor Microenvironment Platform Mimicking the EPR Effect for Rapid Screening of Drug Delivery Systems

Real-time monitoring of tumor drug delivery in vivo is a daunting challenge due to the heterogeneity and complexity of the tumor microenvironment. In this study, we developed a biomimetic microfluidic tumor microenvironment (bMTM) comprising co-culture of tumor and endothelial cells in a 3D environm...

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Publicat a:Sci Rep
Autors principals: Tang, Yuan, Soroush, Fariborz, Sheffield, Joel B., Wang, Bin, Prabhakarpandian, Balabhaskar, Kiani, Mohammad F.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571192/
https://ncbi.nlm.nih.gov/pubmed/28839211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09815-9
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