Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs

Increases in prothrombin time (PT) and international normalised ratio (INR) characterise acute liver injury (ALI) and failure (ALF), yet a wide heterogeneity in clotting abnormalities exists. This study defines evolution of coagulopathy in 10 pigs with acetaminophen (APAP)-induced ALI compared to 3...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lee, Karla Chui Luan, Baker, Luisa, Mallett, Susan, Riddell, Anne, Chowdary, Pratima, Alibhai, Hatim, Chang, Yu-Mei, Priestnall, Simon, Stanzani, Giacomo, Davies, Nathan, Mookerjee, Rajeshwar, Jalan, Rajiv, Agarwal, Banwari
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571150/
https://ncbi.nlm.nih.gov/pubmed/28839178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09508-3
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