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Quantum dot-mediated delivery of siRNA to inhibit sphingomyelinase activites in brain-derived cells

The use of RNAi to suppress protein synthesis offers a potential way of reducing the level of enzymes or the synthesis of mutant toxic proteins but there are few tools currently available for their delivery. To address this problem, bioconjugated quantum dots (QDs) containing a hydrophobic component...

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Detalles Bibliográficos
Publicado en:J Neurochem
Autores principales: Getz, Ted, Qin, Jingdong, Medintz, Igor L., Delehanty, James B., Susumu, Kimihiro, Dawson, Philip E., Dawson, Glyn
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570548/
https://ncbi.nlm.nih.gov/pubmed/27622309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13841
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