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Quantum dot-mediated delivery of siRNA to inhibit sphingomyelinase activites in brain-derived cells

The use of RNAi to suppress protein synthesis offers a potential way of reducing the level of enzymes or the synthesis of mutant toxic proteins but there are few tools currently available for their delivery. To address this problem, bioconjugated quantum dots (QDs) containing a hydrophobic component...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Getz, Ted, Qin, Jingdong, Medintz, Igor L., Delehanty, James B., Susumu, Kimihiro, Dawson, Philip E., Dawson, Glyn
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570548/
https://ncbi.nlm.nih.gov/pubmed/27622309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13841
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