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Efficient and stable production of Modified Vaccinia Ankara virus in two-stage semi-continuous and in continuous stirred tank cultivation systems

One important aim in cell culture-based viral vaccine and vector production is the implementation of continuous processes. Such a development has the potential to reduce costs of vaccine manufacturing as volumetric productivity is increased and the manufacturing footprint is reduced. In this work, c...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tapia, Felipe, Jordan, Ingo, Genzel, Yvonne, Reichl, Udo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570375/
https://ncbi.nlm.nih.gov/pubmed/28837572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182553
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