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A regulatory element that mediates co-operation between a PEA3-AP-1 element and an AP-1 site is required for phorbol ester induction of urokinase enhancer activity in HepG2 hepatoma cells.

We have characterized a transcriptional enhancer of the human urokinase-type plasminogen activator (uPA) gene and found a regulatory element required for co-operation between a PEA3--AP-1 element and an AP-1 site in the enhancer. We designated this regulatory element co-operation mediator (COM). Bot...

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Detalhes bibliográficos
Main Authors: Nerlov, C, De Cesare, D, Pergola, F, Caracciolo, A, Blasi, F, Johnsen, M, Verde, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC557033/
https://ncbi.nlm.nih.gov/pubmed/1330539
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