Immune characterization of the HBHA-specific response in Mycobacterium tuberculosis-infected patients with or without HIV infection

INTRODUCTION: RD1-based Interferon-γ Release Assays (IGRAs) cannot distinguish latent from active tuberculosis (TB) disease. Conversely, a positive response to heparin-binding haemagglutinin (HBHA)-based IGRAs, among TB-infected subjects, correlates with Mycobacterium tuberculosis (Mtb) containment...

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Udgivet i:PLoS One
Main Authors: Chiacchio, Teresa, Delogu, Giovanni, Vanini, Valentina, Cuzzi, Gilda, De Maio, Flavio, Pinnetti, Carmela, Sampaolesi, Alessandro, Antinori, Andrea, Goletti, Delia
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570327/
https://ncbi.nlm.nih.gov/pubmed/28837654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183846
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