Effects of subconjunctival administration of anti-high mobility group box 1 on dry eye in a mouse model of Sjӧgren’s syndrome

PURPOSE: Extracellular high mobility group box 1 (HMGB1) acts as a damage associated molecular pattern molecule through the Toll-like receptor to promote autoreactive B cell activation, which may be involved in the pathogenesis of Sjӧgren’s syndrome. The aim of this study was to investigate the effe...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kim, Kyeong Hwan, Kim, Dong Hyun, Jeong, Hyun Jeong, Ryu, Jin Suk, Kim, Yu Jeong, Oh, Joo Youn, Kim, Mee Kum, Wee, Won Ryang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570279/
https://ncbi.nlm.nih.gov/pubmed/28837629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183678
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