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Cytoplasmic delivery of ribozymes leads to efficient reduction in alpha-lactalbumin mRNA levels in C127I mouse cells.

Ribozymes targeted to five sites along the alpha-lactalbumin (alpha-lac) mRNA were delivered to the cytoplasm of mouse C127I mammary cells using the T7-vaccinia virus delivery system and the amount of alpha-lac mRNA was monitored 24-48 h post-transfection. Three target sites were selected in the alp...

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Foilsithe in:EMBO J
Main Authors: L'Huillier, P J, Davis, S R, Bellamy, A R
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 1992
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC557015/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1425576/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05541.x
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