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The atypical M2 segment of the beta subunit confers picrotoxinin resistance to inhibitory glycine receptor channels.

Purified preparations of the inhibitory glycine receptor (GlyR) contain alpha and beta subunits, which share homologous primary structures and a common transmembrane topology with other members of the ligand-gated ion channel superfamily. Here, a beta subunit-specific antiserum was shown to precipit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pribilla, I, Takagi, T, Langosch, D, Bormann, J, Betz, H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC557003/
https://ncbi.nlm.nih.gov/pubmed/1385113
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