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The multidrug resistance and cystic fibrosis genes have complementary patterns of epithelial expression.

The cystic fibrosis gene product, CFTR, and the multidrug resistance P-glycoprotein (encoded by the MDR1 gene) are structurally related proteins and both are associated with epithelial chloride channel activities. We have compared their cell-specific expression in the rat by in situ hybridization. I...

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Autors principals: Trezise, A E, Romano, P R, Gill, D R, Hyde, S C, Sepúlveda, F V, Buchwald, M, Higgins, C F
Format: Artigo
Idioma:Inglês
Publicat: 1992
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC557002/
https://ncbi.nlm.nih.gov/pubmed/1385112
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