Prevention of Atrial Fibrillation by Using Sarcoplasmic Reticulum Calcium ATPase Pump Overexpression in a Rabbit Model of Rapid Atrial Pacing

BACKGROUND: Recent research suggests that abnormal Ca(2+) handling plays a role in the occurrence and maintenance of atrial fibrillation (AF). Therefore, Ca(2+) release and ingestion depend on properties of the ryanodine receptor (RyR) and sarcoplasmic reticulum Ca(2+)ATPase2a (SERCA2a). This study...

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Udgivet i:Med Sci Monit
Main Authors: Wang, Hong li, Zhou, Xian hui, Li, Zhi qiang, Fan, Ping, Zhou, Qi na, Li, Yao dong, Hou, Yue mei, Tang, Bao peng
Format: Artigo
Sprog:Inglês
Udgivet: International Scientific Literature, Inc. 2017
Fag:
Animal Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569926/
https://ncbi.nlm.nih.gov/pubmed/28811460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.904824
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