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Negative regulation of mitosis by two functionally overlapping PTPases in fission yeast.

We have identified a third protein tyrosine phosphatase (PTPase) gene in fission yeast, pyp2, encoding an 85 kDa protein. Disruption of pyp2 has no impact on cell viability, but pyp2 is essential in strains lacking the 60 kDa pyp1 PTPase. The two pyp PTPases are approximately 42% identical in their...

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Detalhes bibliográficos
Main Authors: Millar, J B, Russell, P, Dixon, J E, Guan, K L
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC556972/
https://ncbi.nlm.nih.gov/pubmed/1464319
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